PICO ANALYSIS OF ANTIBIOTIC EFFICACY IN MULTIDRUG-RESISTANT SHIGELLOSIS (2015–2025): A COMPREHENSIVE DECADE STUDY
Keywords:
Shigella spp., PICO, AMR, Azithromycin, WHO BPPL 2024, XDR, ESBL, ipaH gene.Abstract
Ushbu tadqiqotda 2015–2025 yillar oralig'idagi o'n yillik davrda shigellyoz qo'zg'atuvchilarining antibiotiklarga chidamlilik dinamikasi PICO modeli orqali tahlil qilindi. Tadqiqot davomida 284 ta namunaning PCR tahlili va 172 ta kultura natijalari o'rganildi. Natijalar shuni ko'rsatdiki, Azitromitsinga rezistentlik 71.4% ga yetgan. Maqolada multirezistent (MDR) va keng rezistent (XDR) shtammlarning tarqalish epidemiologiyasi va diagnostik qiyinchiliklar yoritilgan.
References
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