ME'DA OSTI BEZI SARATONINI TASHXISLASHDA ULTRATOVUSH TEKSHIRUVINING AHAMIYATI
Keywords:
me'da osti bezi saratoni, ultratovush tekshiruvi, endoskopik ultratovush, EUS, erta tashxis, pankreatik adenokarsinoma.Abstract
Me'da osti bezi saratoni (MOBS) jahon miqyosida o'lim ko'rsatkichi yuqori bo'lgan xavfli o'smalar qatoriga kiradi. Ko'pchilik hollarda kasallik kech bosqichda aniqlanishi sababli bemorlar uchun prognoz noqulay bo'lib qolmoqda.
Metodologiya: 2019–2024 yillar davomida 87 nafar bemor transabdominal va endoskopik ultratovush (EUS) tekshiruvi o'tkazildi. Natijalar KT va MRT ma'lumotlari hamda patogistologik xulosalar bilan qiyosiy tahlil qilindi.
Asosiy topilmalar: EUS tekshiruvi 2 sm dan kichik o'smalarda sezgirligi 94,2%, o'ziga xosligi 89,7% ni tashkil etdi. Transabdominal UZI ning sezgirligi 72,4% ga teng bo'ldi. EUS me'da osti bezi bosh qismi o'smalarini aniqlashda ayniqsa yuqori samaradorlik ko'rsatdi.
Asosiy xulosa: EUS MOBS ni erta bosqichda tashxislashda yuqori diagnostik aniqlikka ega. Ushbu usulni keng klinik amaliyotga joriy etish bemorlarning omon qolish ko'rsatkichlarini yaxshilashga xizmat qiladi.
References
Dietrich C.F., Arcidiacono P.G., Bhutani M.S. et al. (2019). Endoscopic ultrasound: Clinical use and indications. Digestive Endoscopy, 31(3), 295–308.
Murad F.M., Irani S., Bhutani M.S. (2020). EUS-guided tissue acquisition: Advances and emerging techniques. Gastrointestinal Endoscopy Clinics, 30(3), 517–532.
Venkatesh P.G., Navaneethan U., Vege S.S. (2021). Intraductal papillary mucinous neoplasm and incidentally detected pancreatic cysts. Clinical Gastroenterology and Hepatology, 19(2), 217–228.
Chen W., Zhang Y., Li Q. (2022). Contrast-enhanced ultrasound in the diagnosis of pancreatic cancer: A meta-analysis. Ultrasound in Medicine and Biology, 48(5), 847–858.
Toshmatov A., Karimov Sh., Yusupov N. (2022). Me'da osti bezi o'smalarini ultratovush diagnostikasi: O'zbekiston tajribasi. O'zbekiston tibbiyot jurnali, 4(2), 34–41.
Hewitt M.J., McPhail M.J., Possamai L. et al. (2012). EUS-guided FNA for diagnosis of solid pancreatic neoplasms: A meta-analysis. Gastrointestinal Endoscopy, 75(2), 319–331.
Lennon A.M., Wolfgang C.L., Canto M.I. et al. (2014). The early detection of pancreatic cancer: What will it take to diagnose and treat curable pancreatic neoplasia? Cancer Research, 74(13), 3381–3389.
Mizrahi J.D., Surana R., Valle J.W., Shroff R.T. (2020). Pancreatic cancer. Lancet, 395(10242), 2008–2020.
WHO. (2022). Global Cancer Statistics. International Agency for Research on Cancer. Lyon: IARC Press.
Siegel R.L., Miller K.D., Jemal A. (2023). Cancer Statistics, 2023. CA: A Cancer Journal for Clinicians, 73(1), 17–48.
