NEVROZ VA UNING KLINIK PATOFIZIOLOGIK NEVROLOGIK TAHLILI: SISTEMA, ORGAN, TO‘QIMA, HUJAYRA VA MOLEKULYAR DARAJALARDA O‘ZGARISHLAR

Rakhmonova.G.E Bozorboyeva.F.M  Musinov.A.A.

NEVROZ VA UNING KLINIK PATOFIZIOLOGIK NEVROLOGIK TAHLILI: SISTEMA, ORGAN, TO‘QIMA, HUJAYRA VA MOLEKULYAR DARAJALARDA O‘ZGARISHLAR

Authors

Rakhmonova.G.E Bozorboyeva.F.M Musinov.A.A.

Keywords:

Nevroz, psixoemosional stress, HPA o‘qi, limbik tizim, neyrotransmitter disbalansi, serotonin, noradrenalin, GABA, glutamat, neyroplastisitet, mitoxondrial disfunksiya, oksidlovchi stress, yallig‘lanish, sitokinlar, epigenetik modifikatsiyalar

Abstract

Nevroz – surunkali psixoemosional stress ta’sirida rivojlanadigan, funksional va strukturaviy o‘zgarishlar bilan kechadigan chegara darajasidagi ruhiy buzilish bo‘lib, uning patofiziologiyasi neyrobiologiyaning barcha darajalarini – sistema, organ, to‘qima, hujayra va molekulyar darajalarni qamrab oladi. Ushbu maqolada nevrozning zamonaviy patofiziologik modeli integrativ yondashuv asosida tahlil qilinadi. Asosiy e’tibor stress-gipotalamus-gipofiz-buyrak usti (HPA) o‘qi, limbik tizim, neyrotransmitter disbalansi (serotonin, noradrenalin, GABA, glutamat), neyroplastisitet o‘zgarishlari, mitoxondrial disfunksiya, oksidlovchi stress, yallig‘lanish kaskadlari va epigenetik modifikatsiyalarga qaratilgan.

References

McEwen BS. Neurobiological and systemic effects of chronic stress. Chronic Stress. 2017;1:1–11. DOI: 10.1177/2470547017692328

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Published

2026-05-09

How to Cite

Rakhmonova.G.E Bozorboyeva.F.M Musinov.A.A. (2026). NEVROZ VA UNING KLINIK PATOFIZIOLOGIK NEVROLOGIK TAHLILI: SISTEMA, ORGAN, TO‘QIMA, HUJAYRA VA MOLEKULYAR DARAJALARDA O‘ZGARISHLAR. SAMARALI TA’LIM VA BARQAROR INNOVATSIYALAR JURNALI, 4(5), 150–167. Retrieved from https://innovativepublication.uz/index.php/jelsi/article/view/5802