SUT BEZI SARATONIDA MOLEKULYAR SUBTIPLAR VA ZAMONAVIY DAVOLASH STRATEGIYALARI
Keywords:
Sut bezi saratoni, molekulyar subtiplar, Luminal A, Luminal B, HER2-musbat, uch martalik manfiy saraton.Abstract
Ushbu maqolada sut bezi saratonining asosiy molekulyar subtiplariga (Luminal A, Luminal B, HER2-musbat va uch martalik manfiy subtiplar) xos biologik xususiyatlar, klinik kechish farqlari hamda zamonaviy davolash strategiyalari keng tahlil qilinadi. Shuningdek, maqsadli terapiya, immunoterapiya va shaxsiylashtirilgan yondashuvlarning klinik ahamiyati yoritiladi.
References
Perou C.M., Sørlie T., Eisen M.B. et al. Molecular portraits of human breast tumours // Nature. – 2000. – Vol. 406. – P. 747–752.
Sørlie T., Perou C.M., Tibshirani R. et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses // Proc Natl Acad Sci USA. – 2001. – Vol. 98. – P. 10869–10874.
Waks A.G., Winer E.P. Breast cancer treatment: A review // JAMA. – 2019. – Vol. 321(3). – P. 288–300.
Harbeck N., Penault-Llorca F., Cortes J. et al. Breast cancer // Nature Reviews Disease Primers. – 2019. – Vol. 5. – Article 66.
