CLINICAL PHARMACOLOGY OF DRUGS USED IN THE TREATMENT OF EPILEPTIC SYNDROME
Keywords:
Epileptic syndrome, antiepileptic drugs, pharmacokinetics, pharmacodynamics, monotherapy, polytherapy, seizure control.Abstract
This article provides a comprehensive overview of the clinical
pharmacology of antiepileptic drugs (AEDs) used in the management of epileptic
syndrome. It explores the mechanisms of action, pharmacokinetics, therapeutic indications,
drug selection based on seizure type, and safety profiles of traditional and newer AEDs.
Special emphasis is placed on personalized treatment strategies, drug interactions, and
pharmacoresistance in epilepsy. The article aims to support rational, evidence-based
pharmacological interventions for improved seizure control and patient outcomes.
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