CLINICAL PHARMACOLOGY OF ANTIHYPERTENSIVE DRUGS USED IN THE TREATMENT OF HYPERTENSION

Authors

  • Odiljonova Aziza Bakhtiyorjon kizi Assistant, Department of Pharmacology, Clinical Pharmacology and Medical Biotechnology, ASMI

Keywords:

Antihypertensive drugs, hypertension, ACE inhibitors, calcium channel blockers, beta-blockers, diuretics.

Abstract

This article provides an in-depth analysis of the clinical pharmacology of
antihypertensive drugs commonly used in the treatment of arterial hypertension. The review
covers
classification
of
antihypertensives,
their
mechanisms of action,
pharmacokinetics, clinical indications, and safety profiles. Emphasis is placed on evidence
based therapeutic strategies, individual drug classes, combination therapy, and the
personalization of treatment plans. The article also considers emerging therapies and
pharmacogenomic perspectives relevant to modern hypertension management.

References

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Williams, B., et al. 2018 ESC/ESH Guidelines for the management of arterial

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Burnier, M. Drug adherence in hypertension. – Pharmacol Res. – 2017. – Vol. 125. – P.

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Messerli, F. H., et al. Beta-blockers in hypertension—the Emperor’s new clothes? – Eur

Heart J. – 2017. – Vol. 38, №22. – P. 1719–1723.

Gupta, A. K., et al. Chlorthalidone vs. hydrochlorothiazide: meta-analysis of efficacy and

safety. – Hypertension. – 2010. – Vol. 55, №6. – P. 1364–1370.

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Published

2025-04-30

How to Cite

Odiljonova Aziza Bakhtiyorjon kizi. (2025). CLINICAL PHARMACOLOGY OF ANTIHYPERTENSIVE DRUGS USED IN THE TREATMENT OF HYPERTENSION. SAMARALI TA’LIM VA BARQAROR INNOVATSIYALAR JURNALI, 3(4), 437–443. Retrieved from https://innovativepublication.uz/index.php/jelsi/article/view/2989